Start the New Year Healthier with Detox?
The holidays are behind us. For those who now want to start the new year particularly healthy, we can already see the cry for "Detox" advice in their faces. Tadaa – here we are!
However, we don't want to use this opportunity to recommend the next detox cure to you like many others do. Quite the opposite: we want to explain to you why detoxification is not an acute therapy for a phase characterized by an unhealthy lifestyle.
Rather, detoxification is a vital process that must continuously occur in your body throughout the year to keep you healthy. Learn what this means and how you can ensure that everything runs smoothly.
Which "Toxins" Need to Be Detoxified?
It's impossible to avoid. Through diet, we regularly ingest toxins in certain doses. Have you ever heard of so-called Persistent Organic Pollutants? These hard-to-break environmental toxins include, for example, the pesticide DDT, which was frequently used until the 1970s. But also dioxins and polychlorinated biphenyls, which are sometimes found in farmed salmon during inspections at levels exceeding permitted limits, fall into this category (1).
The problem: when exposed to these toxic substances in high concentrations or over a long period, they can accumulate in fatty tissue, bones, or other body tissues. For this reason, fatty fish like salmon, herring, or eel can be particularly contaminated. The same applies to heavy metals like lead or mercury.
Even if we could somehow escape environmental toxins, we'd be lost without detoxification. Because toxic metabolic byproducts are also generated in normal metabolic processes:
- In protein metabolism, for example, amino acids must be broken down daily. A toxic byproduct is ammonia.
- Another example involves steroid hormones: estrogens must be regularly broken down in the liver, otherwise the delicate hormonal balance gets disrupted. This is also detoxification.
The good news, however, is that our body has numerous ways to handle this. Otherwise, we couldn't survive at all!
The Five Heroes of Detoxification
Liver cells, for example, are able to convert the ammonia from protein metabolism into much less harmful urea, which is then excreted via the kidneys in urine. The intestines, skin, and lungs also play a significant role as excretory organs in eliminating harmful substances.
Among detoxification organs, the liver is a true superhero. It has the ability to transform toxins into non-toxic substances. Of course, this isn't magic that happens instantly.
As part of biotransformation, harmful substances are gradually rebuilt and rendered harmless with the help of numerous enzymes and cofactors. Additionally, many harmful substances are only poorly soluble in water. They must be modified by enzymes so they can be transported away via fluids like urine.
For these processes to work smoothly, your body needs the right building blocks – and that's exactly where you can help!
Even Superheroes Don't Solve Problems Alone
Zeolite, bentonite, or activated charcoal are well-known ingredients for a detox cure. But what do these really contribute to detoxification?
Well, if heavy metals or other environmental toxins are present in food that you're consuming alongside them, they can actually promote detoxification. The volcanic mineral zeolite was able to reduce lead uptake in the intestines by an impressive 90% in one study (2).
However, these powders cannot change toxins already stored in your body. Insufficient data also make it impossible to fully assess the effects of these substances.
What if instead you took a powder that provides you with all the nutrients that help support our detoxification superheroes in their work? This could be, for example, our eduone®, which provides a whole range of detoxification-promoting substances:
- Some B vitamins play an important role in detoxification as cofactors for detoxification enzymes. They are also important for proper methylation, which protects against arsenic.
- Secondary plant compounds like citrus bioflavonoids, from green tea extract, or from chlorella algae (in moderation, not in masses mind you) activate the NRF2 regulator, which stimulates detoxification in the liver and other cells (3,4,5).
- Antioxidants like vitamin E or selenium can neutralize reactive intermediates that arise during biotransformation in the liver (4,5).
- Zinc increases proteins in the liver (metallothioneins) that can bind heavy metals (6).
- Dietary fiber not only promotes gut health – the signaling molecules from your microbiome also reach your detoxification organs! They also reduce the activity of enzymes that would otherwise constantly recirculate substances needing detoxification from the intestines back into the body circulation (7,8).
- Taurine is also considered a superstar of detoxification – this aminosulfonic acid has a special sulfur group that helps your body eliminate toxins and protect itself from them enzymatically (9).
- And several others.
A detoxification-promoting lifestyle extends beyond nutrition: regular sweating is essential! Heavy metals are indeed transported out of the body through sweat (10). When was the last time you visited a sauna? ;-) Exercise works too!
Your Takeaway from This Article Should Be:
A colorful and varied diet combined with ensuring good nutrient supply is essential for the function of your detoxification organs and is far more effective than any overpriced detox cure!
Sources
- Hites RA, Foran JA, Carpenter DO, Hamilton MC, Knuth BA, Schwager SJ. Global assessment of organic contaminants in farmed salmon. Science. January 9, 2004;303(5655):226–9.
- Samekova K, Firbas C, Irrgeher J, Opper C, Prohaska T, Retzmann A, et al. Concomitant oral intake of purified clinoptilolite tuff (G-PUR) reduces enteral lead uptake in healthy humans. Sci Rep. July 20, 2021;11(1):14796.
- Byun HG, Lee JK. Chlorella ethanol extract induced phase II enzyme through NFE2L2 (nuclear factor [erythroid-derived] 2-like 2, NRF2) activation and protected ethanol-induced hepatoxicity. J Med Food. 2015 Feb;18(2):182–9. doi: 10.1089/jmf.2014.3159. Epub 2015 Jan 20.
- Leonardo CC, Doré S. Dietary flavonoids are neuroprotective through Nrf2-coordinated induction of endogenous cytoprotective proteins. Nutr Neurosci. 2011 Sep;14(5):226–36. doi: 10.1179/1476830511Y.0000000013.
- Sun W, Liu X, Zhang H, Song Y, Li T, Liu X, et al. Epigallocatechin gallate upregulates NRF2 to prevent diabetic nephropathy via disabling KEAP1. Free Radic Biol Med. 2017 Jul;108:840–57. doi: 10.1016/j.freeradbiomed.2017.04.365.
- Aydemir TB, Blanchard RK, Cousins RJ. Zinc supplementation of young men alters metallothionein, zinc transporter, and cytokine gene expression in leukocyte populations. Proc Natl Acad Sci U S A. February 7, 2006;103(6):1699–704.
- Kieffer DA, Martin RJ, Adams SH. Impact of Dietary Fibers on Nutrient Management and Detoxification Organs: Gut, Liver, and Kidneys. Advances in Nutrition. November 10, 2016;7(6):1111.
- Reddy BS, Engle A, Simi B, Goldman M. Effect of dietary fiber on colonic bacterial enzymes and bile acids in relation to colon cancer. Gastroenterology. May 1992;102(5):1475–82.
- Naraki K, Keshavarzi M, Razavi BM, Hosseinzadeh H. The protective effects of taurine, a non-essential amino acid, against metals toxicities: a review article. Biol Trace Elem Res. May 13, 2024. doi: 10.1007/s12011-024-04191-8. Online ahead of print.
- Kuan WH, Chen YL, Liu CL. Excretion of Ni, Pb, Cu, As, and Hg in Sweat under Two Sweating Conditions. Int J Environ Res Public Health. April 4, 2022;19(7):4323.